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(PubMed) Bosy-Westphal A, Holzapfel A, Czech N, Muller MJ

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The extract effectively suppressed IgG2a, IgE, eosinophilia, and mucus hypersecretion and significantly inhibited the increase in mRNA expression and Th2-type cytokines, including IL-5 and IL-4 in lung tissue and bronchoalveolar lavage fluid (BALF) in the asthmatic mouse model

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This binding triggers a cascade of events that leads to the production of HGH and IGF-1